Friday, December 13, 2013

Cancers Like it Cool

Brought to you by Angela

Are these mice cuddling to stay warm? Most lab animals live in rooms kept cooler than they find comfortable. If they also have cancer, cool room temperatures can boost their tumors’ growth and spread, new data show.

Courtesy of Kathleen Kokolus and Sandra Sexton

20 comments:

Juliet said...

I think this article was one of the most interesting I've seen so far on the blog. I would like to congratulate Angela on that. I think this article was short but sweet. It cut to the chase, not wasting time discussing other not quite on the topic subjects and used readable language. Cancer studies are one of the most important in this day and age, and although they don't know that this is effective also in the human body, I thought that it was. If the cancers are the same, wouldn't they act the same way in both bodies? But when you look at it closely, we fight it off in different ways, so although the cancers may be the same, which they probably aren't, but the mouse and human cells destroying it aren't, so this may not be true of humans at all. I think this is a great article and a great find.

Erica said...

I find that this article had a great amount of information about what is happening around us. You might think this is only about mice, not about everyone and everything else. If you think that, you are wrong. The discovery of finding that mice develop less tumors when they are in warmer temperatures might help us. Mice have a lot in common with humans. They are mammals and have almost everything that we have. As Juliet said, we might have different ways of attacking cancer. I totally agree with Juliet. On the other hand, we might have the same way of attacking cancer. If this works, then we will be much better off in the world, and know what to do first thing right away. I liked how this article had words at the end that were called power words. They had the words and their definition there. I liked this because whenever I came across a word I didn’t know, I would look at the power words. This was a great article because of the way it stated the information, and what kind of information it had. I would rate this article a 10 out of 10.

Christina said...

This was a very interesting article! If the same effect occurs on a human that occurs on mice, then this study could change our medicines. The part of the article that especially caught my attention was the section where it talked about the temperature having an effect on the medicine. Perhaps we could be giving cancer patients false drugs that are flawed just because we kept the temperature a little low in labs! I was also wondering why the article chose to mention T cells when it mentioned there being less white blood cells because of the temperature because there are three types of lymphocytes (a type of white blood cell that defends the body)—the T cells, B cells and NK cells. These types of cells all defend the body and there are also many different other kinds of white blood cells besides lymphocytes such as monocytes and neutrophil. However, this article chose to mention a decrease in T cells. Are T cells more effective in fighting cancer than other white blood cells?

Alec T said...

I think that these findings can be very useful in helping patients survive cancer. I agree with Erica and I think we should test to see if this technique of warming the room works on humans too. Also I think that Christina is right and this could possibly involve many other medicines or diseases. Cancer studies are very important so this could be vital information so we can come nearer to finding a cure for cancer. I think that even though mice were being tested, humans will probably react the same way if we keep them at warm temperatures inside of hospitals. Hopefully we can soon find a cure for cancer.

Alec T said...

I think that these findings can be very useful in helping patients survive cancer. I agree with Erica and I think we should test to see if this technique of warming the room works on humans too. Also I think that Christina is right and this could possibly involve many other medicines or diseases. Cancer studies are very important so this could be vital information so we can come nearer to finding a cure for cancer. I think that even though mice were being tested, humans will probably react the same way if we keep them at warm temperatures inside of hospitals. Hopefully we can soon find a cure for cancer.

Alec T said...

I think that these findings can be very useful in helping patients survive cancer. I agree with Erica and I think we should test to see if this technique of warming the room works on humans too. Also I think that Christina is right and this could possibly involve many other medicines or diseases. Cancer studies are very important so this could be vital information so we can come nearer to finding a cure for cancer. I think that even though mice were being tested, humans will probably react the same way if we keep them at warm temperatures inside of hospitals. Hopefully we can soon find a cure for cancer.

Alec T said...

I think that these findings can be very useful in helping patients survive cancer. I agree with Erica and I think we should test to see if this technique of warming the room works on humans too. Also I think that Christina is right and this could possibly involve many other medicines or diseases. Cancer studies are very important so this could be vital information so we can come nearer to finding a cure for cancer. I think that even though mice were being tested, humans will probably react the same way if we keep them at warm temperatures inside of hospitals. Hopefully we can soon find a cure for cancer.

Alec T said...

Sorry my comment posted four times... that's not the first time it's happened.

Ali M. said...

I found this article to be a very interesting article. I never knew that an effect in temperature could affect how cancer grows. I think that this might be a was to help cancer patients. Thinking for a while I realized that there are flaws in this method to. Could it be reversed? If a human or animal was used to cold temperatures do you think it would help to make it cold in the room rather than hot? I'm not sure. And do you think that this only works on certain types of cancers and not all? I was researching on how heat is being used now to help cancer and I found out that hyperthermia is a way that they are now using to treat certain cancers. The doctors either use a very hot temperature to destroy a small area of cells like a tumor or they are raising the temperature in a part of your body or your whole body by a couple degrees. This doesn't cure cancer but it helps other treatments like radiation, immunotherapy, or chemotherapy to work better. Overall I enjoyed this article and I think we might be on our wat to finding a cure to cancer.

Lilah said...

Agreeing with Juliet, cancer is a very big problem in our world and every discovery related to curing it counts. This discovery could change the world's way of curing cancer, cure it faster, and even effect the amount of cancers overall. I do think that this should be tested on humans, however I think it should be done by somehow extracting the cancer cells. I'm not sure if the mice mind, but I sure wouldn't want to be tested on if I had cancer. That would just be another bad thing to add onto the pile of struggling with cancer. Anyways, I give the article 9 out of 10 stars for its perfect length and important and intriguing topic.

Will said...

I think that it is a very important discovery that colder temperatures spur on cancer, at least for mice. If research and studying have occurred in cold rooms instead of warm ones, this could change the results of medicines made based off of the information found where cancer grows more quickly. It might be hard to find any perfect research because the cancer can either grow much quicker or much slower. This could make it difficult. The cold can also kill T cells, which can hold off or even kill tumors. Additionally, cells that are known to partially turn off immunity were abundant near these tumors. I think that the researchers should move the mice that were being tested on to a warmer environment, do research there, and compare the different findings. I believe that this would be beneficial to having accurate research on cancer.

Clyde C. said...

This is a great discovery but, I am a little puzzled about how the people that discovered this can get the information out to those that need to hear it. Not everyone with cancer can live in a hot climate, either. Of course this discovery is one of great value and something that I think will be used in the near future.

Shirell said...

Firstly, I would like to comment that I found it a little disturbing that the researchers are now putting mice into the cold environments, and just watching the tumors grow in them, instead of putting them in a warmer environment to help them fight off the tumors. When I was reading it seemed as though these mice are just born with tumors. They said that the mice in warmer environments are fighting them off better. Well, if the heat is helping, why did they get the tumors in the first place. I think that these researchers may be trying to have these mice get tumors. I know that this is for scientific research, but I still wish for another way to test this type of thing.

Kristin said...

I totally agree with Juliet on this one, this is one of the most interesting articles on the blog. Thanks Angela! I agree with Juliet (again) on how Cancer study is important now. Thousands of people have died from it and studying it might draw us closer to a cure. I really enjoyed this article, now I am more interested in cancer studies. I enjoyed this wonderful blog post, and thanks again Angela!

Jonas said...

I would also like to congratulate Angela on this for finding such an interesting and mouth-watering article to read. As we know, cancer studies today are really important and although they don't know that this effects the human body, I also (agreeing with Juliet) though it was. We have many ways of fighting back with cancer, but even so there is not much we can do about cancer. I think that these findings can be very useful in helping patients survive cancer, which is good considering the thousands and thousands of people already on the face of the earth who have fallen as a victim to cancer.

Jonas said...

I would also like to congratulate Angela on this for finding such an interesting and mouth-watering article to read. As we know, cancer studies today are really important and although they don't know that this effects the human body, I also (agreeing with Juliet) though it was. We have many ways of fighting back with cancer, but even so there is not much we can do about cancer. I think that these findings can be very useful in helping patients survive cancer, which is good considering the thousands and thousands of people already on the face of the earth who have fallen as a victim to cancer.

Jonas said...

srry for posting twice, glitch.

Yvette said...

When I read this article, I was happy and surprised at the same time. I was happy because the more we know about cancer, the better we will be able to treat it in the future. The best way to discover treatments that work against the disease is to test new methods and procedures on mice. Mice share with humans 97.5% of usable DNA and unfortunately for the mice, they are easy and cheap to breed and reproduce quickly. What this article focused on is a recent study, suggesting that the growth of cancer in these mice is influenced by the temperature at which they are kept. Since we test on mice, how do we know if the results will also apply to other mammals such as us? What the study indicated is that the mice maintain a constant body temperature no matter how hot or cold the room is. Mice who are kept in a cooler environment make up for it by producing more of their own body heat. This process is called thermogenesis, but it also indicates that by doing so, thermogenesis slows down immunity. The mice do not have as much energy as they used to have to fight the tumors. This leads to the tumors growing, and the mouse dying with cancer. Will human beings with cancer react in the same way as the mice? This article suggests that human beings suffering with cancer may benefit from being kept in warmer rooms than before, and that some cancer drugs which create "deep chills" in patients may be doing more harm than good. More studies will be needed to determine the effects of temperature on various cancer treatments that are both given to mice and human beings.

Jack said...

I found this article fascinating. I never thought that something as simple as room temperature could affect cancer, or the effectiveness of cancer drugs. It makes me wonder about all the studies that have been done without working with this factor. Are they useless now? But, if cold is a form of physiological stress, I wonder if extreme heat is too? If the researchers are correct that simply avoiding cold and other sources of stress can help cancer patients, that would be an amazing discovery.

JP said...

I think that this is quite interesting because if it being cold causes more tumor growth, do hotter temperatures result in less tumor growth? This is a great discovery because cancer is one of the most difficult kinds of diseases there are. If my theory about the hot temperatures is correct, we might be able to find a way to treat cancer that is not as painful as chemotherapy. Overall this article was great and could possibly change the way we look at cancer.